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Crohn's Disease News

Research Review
Subcutaneous Infliximab Effective Across Ileal and Colonic Crohn’s Disease
04/02/2026
Jessica Garlewicz
Post-hoc analysis shows that endoscopic responses to subcutaneous infliximab were observed across all intestinal segments, including the terminal ileum.
Post-hoc analysis shows that endoscopic responses to subcutaneous infliximab were observed across all intestinal segments, including the terminal ileum.
Post-hoc analysis shows that...
04/02/2026
Advances in Inflammatory Bowel Disease Network
Research Review
Upper GI Crohn’s Disease Remains Underrecognized, Lacks Standardized Guidance
04/02/2026
Jessica Garlewicz
A recent review noted a lack of consistent diagnostic definitions across modalities, complicating clinical interpretation and research comparisons.
A recent review noted a lack of consistent diagnostic definitions across modalities, complicating clinical interpretation and research comparisons.
A recent review noted a lack of...
04/02/2026
Advances in Inflammatory Bowel Disease Network
Research Review
Advanced Therapies Show Reduced Efficacy in Ileal vs Colonic Crohn’s Disease
04/02/2026
Jessica Garlewicz
Isolated ileal Crohn’s has proved difficult to for most currently available advanced therapies, researchers found.
Isolated ileal Crohn’s has proved difficult to for most currently available advanced therapies, researchers found.
Isolated ileal Crohn’s has...
04/02/2026
AIBD NP/PA Institute
Research Summary
High Endoscopic Recurrence Rates Seen After Segmental Colectomy in Crohn’s Disease
03/18/2026
Jessica Garlewicz
Risk stratification and postoperative prophylaxis are important for patients who have undergone segmental colectomy for Crohn’s disease, researchers reported.
Risk stratification and postoperative prophylaxis are important for patients who have undergone segmental colectomy for Crohn’s disease, researchers reported.
Risk stratification and...
03/18/2026
Advances in Inflammatory Bowel Disease Network
Research Summary
Most Patients With Crohn’s Disease Meet Moderate-to-High Risk Criteria
03/18/2026
Jessica Garlewicz
The findings of a recent claims analysis highlight gaps between risk burden and treatment patterns in real-world practice.
The findings of a recent claims analysis highlight gaps between risk burden and treatment patterns in real-world practice.
The findings of a recent claims...
03/18/2026
Advances in Inflammatory Bowel Disease Network
Research Highlights
Infliximab and Ustekinumab Show Comparable Effectiveness in Biologic-Naïve Crohn’s Disease
01/14/2026
Jessica Garlewicz
Endoscopic response, transmural remission, and transmural response rates showed no significant differences between treatment groups at either assessment window.
Endoscopic response, transmural remission, and transmural response rates showed no significant differences between treatment groups at either assessment window.
Endoscopic response, transmural...
01/14/2026
Advances in Inflammatory Bowel Disease Network
Research Highlights
Ustekinumab and Vedolizumab Show Safety and Efficacy for Crohn’s Disease of the Pouch
09/18/2025
Jessica Garlewicz
Ustekinumab may offer a more durable and effective approach in managing this challenging patient population, new research shows.
Ustekinumab may offer a more durable and effective approach in managing this challenging patient population, new research shows.
Ustekinumab may offer a more...
09/18/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Upadacitinib Improves Outcomes in Fistulizing Crohn’s Disease
09/04/2025
Rebecca Mashaw
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Pelvic MRI Detects Subclinical Perianal Disease in Pediatric Crohn’s Disease
09/04/2025
Jessica Garlewicz
The study highlights a diagnostic blind spot in pediatric CD management and supports adding baseline pelvic MRI to initial workup, even in the absence of perianal symptoms.
The study highlights a diagnostic blind spot in pediatric CD management and supports adding baseline pelvic MRI to initial workup, even in the absence of perianal symptoms.
The study highlights a...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Mirikizumab Improves Quality of Life and Work Productivity in Moderate to Severe Crohn’s Disease
09/04/2025
Jessica Garlewicz
Study findings highlight mirikizumab as a therapeutic option that delivers not only symptom relief but also sustained improvements in quality of life and functional outcomes for patients with moderate to severe CD.
Study findings highlight mirikizumab as a therapeutic option that delivers not only symptom relief but also sustained improvements in quality of life and functional outcomes for patients with moderate to severe CD.
Study findings highlight...
09/04/2025
Advances in Inflammatory Bowel Disease Network

Latest News

Research Review
Upper GI Crohn’s Disease Remains Underrecognized, Lacks Standardized Guidance
04/02/2026
Jessica Garlewicz
A recent review noted a lack of consistent diagnostic definitions across modalities, complicating clinical interpretation and research comparisons.
A recent review noted a lack of consistent diagnostic definitions across modalities, complicating clinical interpretation and research comparisons.
A recent review noted a lack of...
04/02/2026
Advances in Inflammatory Bowel Disease Network
Research Summary
Advanced Therapy May Reduce Antibiotic Dependence in Chronic Pouchitis After IPAA
03/18/2026
Jessica Garlewicz
These findings support considering immune-mediated therapy in selected patients although more research is needed to identify the patients likely to benefit most from advanced therapy.
These findings support considering immune-mediated therapy in selected patients although more research is needed to identify the patients likely to benefit most from advanced therapy.
These findings support...
03/18/2026
Advances in Inflammatory Bowel Disease Network
Research Review
New Meta-Analysis Highlights Burden of MASLD Among IBD Patients
02/03/2026
Rebecca Mashaw
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from...
02/03/2026
Gastroenterology
News
Medicare Will Cover GLP-1s for Obesity Under Deal with Pharma
11/06/2025
Rebecca Mashaw
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said...
11/06/2025
Advances in Inflammatory Bowel Disease Network
FDA alert
FDA Alert
FDA Approves Updated Indication for Upadacitinib in IBD
10/14/2025
Rebecca Mashaw
The new indication allows for upadacitinib therapy among patients who have received any approved systemic therapy for IBD “in the event TNF blockers are clinically inadvisable."
The new indication allows for upadacitinib therapy among patients who have received any approved systemic therapy for IBD “in the event TNF blockers are clinically inadvisable."
The new indication allows for...
10/14/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Concomitant Medications Do Not Alter Efficacy of Advanced Therapies in Ulcerative Colitis, Study Finds
09/18/2025
Jessica Garlewicz
New study findings suggest that most baseline concomitant therapies do not require modification or exclusion when initiating advanced therapy in clinical trial settings.
New study findings suggest that most baseline concomitant therapies do not require modification or exclusion when initiating advanced therapy in clinical trial settings.
New study findings suggest that...
09/18/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Persistent Prothrombotic State Observed in Patients With ASUC
09/04/2025
Rebecca Mashaw
New findings show patients with acute severe ulcerative colitis remain at elevated thrombotic risk for up to 12 weeks post-hospitalization.
New findings show patients with acute severe ulcerative colitis remain at elevated thrombotic risk for up to 12 weeks post-hospitalization.
New findings show patients with...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Upadacitinib Improves Outcomes in Fistulizing Crohn’s Disease
09/04/2025
Rebecca Mashaw
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Pelvic MRI Detects Subclinical Perianal Disease in Pediatric Crohn’s Disease
09/04/2025
Jessica Garlewicz
The study highlights a diagnostic blind spot in pediatric CD management and supports adding baseline pelvic MRI to initial workup, even in the absence of perianal symptoms.
The study highlights a diagnostic blind spot in pediatric CD management and supports adding baseline pelvic MRI to initial workup, even in the absence of perianal symptoms.
The study highlights a...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Mirikizumab Improves Quality of Life and Work Productivity in Moderate to Severe Crohn’s Disease
09/04/2025
Jessica Garlewicz
Study findings highlight mirikizumab as a therapeutic option that delivers not only symptom relief but also sustained improvements in quality of life and functional outcomes for patients with moderate to severe CD.
Study findings highlight mirikizumab as a therapeutic option that delivers not only symptom relief but also sustained improvements in quality of life and functional outcomes for patients with moderate to severe CD.
Study findings highlight...
09/04/2025
Advances in Inflammatory Bowel Disease Network

Latest Podcasts

IBD Drive time logo
Expert Insights
IBD Drive Time: The Best of ECCO 2026
03/25/2026
Raymond Cross, MD; Sara Horst, MD; Jordan Axelrad, MD
Host Raymond Cross, MD, is joined by Drs Sara Horst and Jordan Axelrad to review the findings of their picks for the best presentations from the European Crohn's and Colitis Organization meeting held earlier this year.
Host Raymond Cross, MD, is joined by Drs Sara Horst and Jordan Axelrad to review the findings of their picks for the best presentations from the European Crohn's and Colitis Organization meeting held earlier this year.
Host Raymond Cross, MD, is...
03/25/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: Shirley Cohen-Mekelburg, MD on Self-Care for IBD Patients
03/17/2026
Shirley Cohen-Mekelburg; Raymond Cross, MD
Host Raymond Cross, MD, calls on Dr Shirley Mekelburg-Cohen to discuss the importance of self-care among patients with IBD, what self-care consists of, and how to help patients learn to partner with their clinicians in controlling their...
Host Raymond Cross, MD, calls on Dr Shirley Mekelburg-Cohen to discuss the importance of self-care among patients with IBD, what self-care consists of, and how to help patients learn to partner with their clinicians in controlling their...
Host Raymond Cross, MD, calls on...
03/17/2026
Advances in Inflammatory Bowel Disease Network
New IBD Logo
Expert Insights
IBD Drive Time: James Lewis, MD, on Dysplasia Surveillance in IBD
02/23/2026
Raymond Cross, MD; James D. Lewis, MD
Dr James Lewis from the University of Pennsylvania and host Dr Raymond Cross discuss the risk of colon cancer among patients with inflammatory bowel disease, the importance of appropriate surveillance, and special considerations for choosing...
Dr James Lewis from the University of Pennsylvania and host Dr Raymond Cross discuss the risk of colon cancer among patients with inflammatory bowel disease, the importance of appropriate surveillance, and special considerations for choosing...
Dr James Lewis from the...
02/23/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: Raymond Cross, MD, on Ostomy Complications
01/13/2026
Raymond Cross, MD; Sara Horst, MD
In this episode of IBD Drive Time, Dr Raymond Cross switches seats and acts as the guest with Sara Horst, MD, as host, to discuss the complexities of ostomy complications.
In this episode of IBD Drive Time, Dr Raymond Cross switches seats and acts as the guest with Sara Horst, MD, as host, to discuss the complexities of ostomy complications.
In this episode of IBD Drive...
01/13/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Conference Coverage
IBD Drive Time: The Best of ACG With Dr Sara Horst
12/01/2025
Raymond Cross, MD; Sara Horst, MD
Dr Sara Horst joins IBD Drive Time host Dr Raymond Cross to review their choices for the best presentations from the American College of Gastroenterology annual meeting.
Dr Sara Horst joins IBD Drive Time host Dr Raymond Cross to review their choices for the best presentations from the American College of Gastroenterology annual meeting.
Dr Sara Horst joins IBD Drive...
12/01/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive Time
Podcast
IBD Drive Time: Freddy Caldera, MD, on Vaccines for Patients With IBD
11/03/2025
Raymond Cross, MD; Freddy Caldera, DO
Freddy Caldera, DO, returns to talk to IBD Drive Time host Raymond Cross, MD, about the best current recommendations for patients with IBD in the midst of controversy and confusion.
Freddy Caldera, DO, returns to talk to IBD Drive Time host Raymond Cross, MD, about the best current recommendations for patients with IBD in the midst of controversy and confusion.
Freddy Caldera, DO, returns to...
11/03/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive Time
Podcast
IBD Drive Time: Megan Riehl, PsyD, on Mental Health and IBD
10/22/2025
Raymond Cross, MD; Megan Riehl, PsyD
Clinical psychologist Megan Riehl, Psy D, talks with IBD Drive Time host Raymond Cross, MD, about the prevalence of anxiety and depression and even post-traumatic stress disorder among patients with inflammatory bowel disease--and how...
Clinical psychologist Megan Riehl, Psy D, talks with IBD Drive Time host Raymond Cross, MD, about the prevalence of anxiety and depression and even post-traumatic stress disorder among patients with inflammatory bowel disease--and how...
Clinical psychologist Megan...
10/22/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive Time
Podcast
IBD Drive Time: Florian Rieder, MD, on Stricturing and Penetrating Crohn's Disease
10/06/2025
Raymond Cross, MD; Florian Rieder
Host Raymond Cross, MD, welcomes back Dr Florian Rieder, an internationally recognized expert in penetrating and stricturing complications of Crohn's disease, to talk about diagnosing, performing endoscopy, and treating this challenging...
Host Raymond Cross, MD, welcomes back Dr Florian Rieder, an internationally recognized expert in penetrating and stricturing complications of Crohn's disease, to talk about diagnosing, performing endoscopy, and treating this challenging...
Host Raymond Cross, MD, welcomes...
10/06/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Jason Schairer, MD, on Extraintestinal Manifestations in IBD
09/25/2025
Jason Schairer, MD; Raymond Cross, MD
Host Raymond Cross, MD, and guest Dr Jason Schairer discuss the varieties of extraintestinal manifestations that may be seen in patients with IBD, how to diagnose them and when to rely on colleagues in dermatology, ophthalmology, and...
Host Raymond Cross, MD, and guest Dr Jason Schairer discuss the varieties of extraintestinal manifestations that may be seen in patients with IBD, how to diagnose them and when to rely on colleagues in dermatology, ophthalmology, and...
Host Raymond Cross, MD, and...
09/25/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
Ryan Ungaro, MD, on Perturbances in Metabolic Pathways in IBD
09/02/2025
Raymond Cross, MD; Ryan Ungaro
Dr Raymond Cross discusses with Dr Ryan Ungaro how the Mount Sinai Crohn's and Colitis Registry, a prospective observational cohort, is being studied to determine if its detailed clinical information and omics data collected can identify new...
Dr Raymond Cross discusses with Dr Ryan Ungaro how the Mount Sinai Crohn's and Colitis Registry, a prospective observational cohort, is being studied to determine if its detailed clinical information and omics data collected can identify new...
Dr Raymond Cross discusses with...
09/02/2025
Advances in Inflammatory Bowel Disease Network

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